Description

N(8)-Aziridinylspermidine is a specialized polyamine derivative containing an aziridine functional group, which is a key structural feature for its biological activity. This compound is primarily valued as a critical research chemical and pharmaceutical intermediate in the development of novel therapeutic agents. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who are focused on oncology research, enzyme inhibition studies, and the synthesis of targeted molecular probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel anticancer agents and enzyme inhibitors targeting polyamine metabolism.
• Biochemical Research: Used as a molecular tool to study polyamine function, cellular proliferation, and apoptosis mechanisms in cancer biology.
• Enzyme Inhibition Studies: Serves as a potent inhibitor for specific enzymes in the polyamine biosynthetic pathway, such as spermidine/spermine N1-acetyltransferase (SSAT).
• Antiproliferative Agent Development: Investigated for its direct cytotoxic properties and potential in developing chemotherapeutic drugs.
• Life Science Reagent: Utilized in academic and industrial R&D laboratories for probing biological pathways and validating drug targets.
• Precision Chemical Synthesis: Employed in the production of high-value, complex molecules for clinical trial materials and reference standards.

Basic Information

Product Name	N(8)-Aziridinylspermidine
CAS No.	154264-47-8
Molecular Formula	C9H21N5
Molecular Weight	199.30 g/mol
Synonyms	N8-Aziridinylspermidine; 1-Aziridinepropanamine, N-(3-aminopropyl)-; N-(3-Aminopropyl)-1-aziridinepropanamine; N1-(3-Aminopropyl)-N8-(aziridin-1-yl)-1,8-diaminooctane (alternative representation); Aziridinylspermidine; Spermidine aziridine derivative; CAS 154264-47-8
EINECS	Contact for details

Quality Control

Our N(8)-Aziridinylspermidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with standards expected for pharmaceutical intermediates and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.