Description

N(1)-Aziridinylspermidine is a specialized synthetic polyamine derivative containing an aziridine functional group. This compound is valued in advanced research and development for its role as a key intermediate in the synthesis of biologically active molecules and novel polymers. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and academic institutions engaged in medicinal chemistry and materials science. Its unique structure makes it a critical building block for creating targeted molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential therapeutic agents, including enzyme inhibitors and targeted drug conjugates.
• Bioconjugation Chemistry: Used in the development of linker molecules for antibody-drug conjugates (ADCs) and other targeted delivery systems due to its reactive aziridine moiety.
• Polymer Science: Acts as a cross-linking agent or monomer in the production of specialty polymers with tailored properties for coatings or biomedical applications.
• Agrochemical Research: Employed in the design and synthesis of novel crop protection agents and plant growth regulators.
• Biochemical Probe Development: Utilized to create molecular probes for studying polyamine metabolism and cellular processes in life science research.
• Material Surface Modification: Applied in surface functionalization protocols to introduce reactive amine groups onto various substrates.

Basic Information

Product Name	N(1)-Aziridinylspermidine
CAS No.	154264-46-7
Molecular Formula	C9H21N5
Molecular Weight	199.30 g/mol
Synonyms	1-(2-Aminoethyl)aziridine, N-(3-Aminopropyl)-; N1-(2-Aminoethyl)aziridine, N-(3-Aminopropyl)-; N1-Aziridinylspermidine; Aziridinylspermidine; Spermidine, N-(2-aminoethyl)aziridine derivative; 1-Aziridino-4,8-diazaoctane; UNII-7VQ54V3E0E
EINECS	Contact for details

Quality Control

Our N(1)-Aziridinylspermidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support compliance with relevant regulatory frameworks for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.