Description

3-Bromo-2-Chloro-5-Methyl-Benzoic Acid is a high-purity halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for precise molecular modifications in the development of complex chemical entities. It is primarily sought after by research institutions and industrial R&D departments engaged in pharmaceutical, agrochemical, and material science applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its halogenated structure contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized polymers and liquid crystalline materials with specific electronic or optical properties.
• Organic Electronics: Acts as a building block for electron-deficient aromatic units in the synthesis of organic semiconductors and charge-transport materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, multi-substituted benzoic acid frameworks.

Basic Information

Product Name	3-Bromo-2-Chloro-5-Methyl-Benzoic Acid
CAS No.	154257-78-0
Molecular Formula	C8H6BrClO2
Molecular Weight	249.49 g/mol
Synonyms	3-Bromo-2-chloro-5-methylbenzoic acid; 2-Chloro-3-bromo-5-methylbenzoic acid; 5-Methyl-3-bromo-2-chlorobenzoic acid; Benzoic acid, 3-bromo-2-chloro-5-methyl-; 154257-78-0; 3-Bromo-2-chloro-p-toluic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-5-Methyl-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.