Description

2-Amino-4-Pentynoic Acid Ethyl Ester Hcl is a specialized alkyne-functionalized amino acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both an amino acid ester and a terminal alkyne group, makes it a versatile intermediate for constructing complex molecular architectures through click chemistry and peptide coupling reactions. This high-purity compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and materials science who require reliable, high-quality intermediates for their innovative projects.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and neurology.
• Peptidomimetics & Bioconjugation: Used to introduce alkyne handles into peptide chains for subsequent modification via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Chemical Biology Probes: Enables the synthesis of activity-based probes and labeled compounds for studying enzyme mechanisms and protein interactions.
• Agrochemical Research: Serves as a building block for developing new crop protection agents with novel modes of action.
• Materials Science: A precursor for functionalized polymers and smart materials where precise molecular architecture is required.
• Academic & Industrial R&D: A valuable reagent for methodological studies in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Amino-4-Pentynoic Acid Ethyl Ester Hcl
CAS No.	154145-91-2
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	Ethyl 2-Amino-4-pentynoate Hydrochloride; Ethyl 2-Amino-4-pentynoate HCl; 4-Pentynoic acid, 2-amino-, ethyl ester, hydrochloride; L-2-Amino-4-pentynoic acid ethyl ester hydrochloride; (S)-2-Amino-4-pentynoic acid ethyl ester hydrochloride; Propargylglycine ethyl ester hydrochloride; 2-Amino-hex-4-ynoic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Pentynoic Acid Ethyl Ester Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.