Description

1-Cyclopropyl-6,7-Difluoro-1,4-Dihydro-8-Hydroxy-4-Oxo-3-Quinolinecarboxylic Acid is a high-purity pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of advanced fluoroquinolone antibiotics, enabling the development of potent antimicrobial agents. It is essential for manufacturers in the active pharmaceutical ingredient (API) and fine chemical sectors seeking reliable, high-quality raw materials for complex synthesis processes.

Application

This advanced chemical intermediate is primarily utilized in the research, development, and commercial production of pharmaceutical compounds. Key application scenarios include:

• Synthesis of Fluoroquinolone Antibiotics: A key precursor for manufacturing next-generation broad-spectrum antimicrobial agents.
• Active Pharmaceutical Ingredient (API) Development: Used in the chemical synthesis of complex drug molecules targeting bacterial infections.
• Pharmaceutical Research & Process Chemistry: Employed in laboratory-scale research and process optimization for new drug candidates.
• Fine Chemical Manufacturing: Serves as a specialized building block for producing high-value, complex organic molecules.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs engaged in the production of antibiotic APIs for global markets.

Basic Information

Item	Details
Product Name	1-Cyclopropyl-6,7-Difluoro-1,4-Dihydro-8-Hydroxy-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	154093-72-8
Molecular Formula	C13H9F2NO4
Molecular Weight	281.21 g/mol
Synonyms	6,7-Difluoro-1-cyclopropyl-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy-4-oxo-; Difluoro Cyclopropyl Quinolone Carboxylic Acid; Quinolone Carboxylic Acid Derivative; Antibiotic Intermediate DFQ; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6,7-Difluoro-1,4-Dihydro-8-Hydroxy-4-Oxo-3-Quinolinecarboxylic Acid is produced under a strict quality management system. The product undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every batch upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.