Description

p-[[2-Cyclopropyl-4-(4-Fluorophenyl)-3-Quinolinyl]Methyl]Phosphonic Acid Diethyl Ester is a high-value, organophosphorus chemical intermediate characterized by its complex quinoline-based structure. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and specialty fine chemicals. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Serves as a sophisticated scaffold for developing new-generation pesticides and herbicides with specific modes of action.
• Chemical Biology Probe Development: Used in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized phosphonate-based ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or electronic properties.

Basic Information

Product Name	p-[[2-Cyclopropyl-4-(4-Fluorophenyl)-3-Quinolinyl]Methyl]Phosphonic Acid Diethyl Ester
CAS No.	154057-57-5
Molecular Formula	C23H23FNO3P
Molecular Weight	411.41 g/mol
Synonyms	Diethyl ({[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl})phosphonate; Phosphonic acid, P-[[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]-, diethyl ester; 154057-57-5; 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinylmethylphosphonic acid diethyl ester; Diethyl (2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methylphosphonate
EINECS	Contact for details

Quality Control

Our production of p-[[2-Cyclopropyl-4-(4-Fluorophenyl)-3-Quinolinyl]Methyl]Phosphonic Acid Diethyl Ester adheres to stringent quality management systems, ensuring batch-to-batch consistency for research and scale-up activities. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We commit to supply chain transparency and regulatory support for global compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and moisture. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.