Description

3-Bromo-5-(n-Boc)Aminomethylisoxazole is a high-value, protected heterocyclic building block essential for modern organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those containing the isoxazole pharmacophore.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries.
• Peptidomimetics & PROTACs: Serves as a crucial component in the design of peptide mimics and proteolysis-targeting chimeras (PROTACs).
• Agrochemical Research: Intermediate in the development of new herbicides and fungicides.
• Chemical Biology Probes: Utilized for labeling and studying biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific molecule assembly.

Basic Information

Product Name	3-Bromo-5-(n-Boc)Aminomethylisoxazole
CAS No.	154016-57-6
Molecular Formula	C10H15BrN2O3
Molecular Weight	291.14 g/mol
Synonyms	3-Bromo-5-[(tert-butoxycarbonyl)aminomethyl]isoxazole; tert-Butyl N-[(3-bromo-1,2-oxazol-5-yl)methyl]carbamate; 5-(Boc-aminomethyl)-3-bromoisoxazole; 3-Bromo-5-(Boc-aminomethyl)isoxazole; 1,2-Oxazole, 3-bromo-5-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-; Boc-AMBr-Isoxazole; (3-Bromo-isoxazol-5-ylmethyl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(n-Boc)Aminomethylisoxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.