Description

Ketodeoxynonulosonic Acid is a high-purity, advanced biochemical intermediate, also known as KDN. This compound is a key structural analog of sialic acids, offering significant value in glycobiology research and the development of novel bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise tools for studying carbohydrate-protein interactions, metabolic pathways, and for synthesizing glycoconjugates.

Application

• Glycobiology Research: A critical tool for studying sialic acid biology, enzyme kinetics (sialidases, sialyltransferases), and cell surface recognition processes.
• Pharmaceutical Intermediate: Used in the synthesis of novel glycomimetics, antiviral agents, and anti-inflammatory compounds targeting sialic acid-mediated pathways.
• Diagnostic Reagent Development: Serves as a standard or inhibitor in assays for detecting sialidase activity or characterizing carbohydrate-binding proteins (lectins).
• Bioconjugation & Probe Synthesis: Acts as a building block for creating labeled probes (e.g., fluorescent, biotinylated) for imaging and detection applications in cellular studies.
• Enzymology Studies: Employed as a substrate or inhibitor to investigate the specificity and mechanism of glycosyltransferases and other carbohydrate-processing enzymes.
• Nutritional & Cosmetic Science: Investigated for potential applications in functional ingredients that modulate cell surface properties.

Basic Information

Product Name	Ketodeoxynonulosonic Acid
CAS No.	153666-19-4
Molecular Formula	C9H15NO9
Molecular Weight	281.22 g/mol
Synonyms	KDN; 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonic Acid; 3-Deoxy-D-glycero-D-galacto-nonulosonic Acid; Ketodeoxynononic Acid; 2-Keto-3-deoxy-D-glycero-D-galacto-nononic Acid
EINECS	Contact for details

Quality Control

Our Ketodeoxynonulosonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.