Description

4-[3-(Trifluoromethyl)Phenyl]Semicarbazide Hydrochloride is a specialized organic intermediate featuring a trifluoromethylphenyl group attached to a semicarbazide core. This compound matters for its role as a critical building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to incorporate this specific trifluoromethyl-substituted phenyl moiety into target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes and labeled compounds used in biochemical assays and diagnostic research.
• Material Science Applications: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new synthetic pathways involving semicarbazide derivatives.

Basic Information

Product Name	4-[3-(Trifluoromethyl)Phenyl]Semicarbazide Hydrochloride
CAS No.	153513-69-0
Molecular Formula	C8H9F3N3O • HCl
Molecular Weight	255.63 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]semicarbazide hydrochloride; 3-Trifluoromethylphenylsemicarbazide hydrochloride; 4-(3-Trifluoromethylphenyl)semicarbazide HCl; 1-(3-Trifluoromethylphenyl)semicarbazide hydrochloride; (3-Trifluoromethylphenyl)carbamoylhydrazine hydrochloride; m-Trifluoromethylphenylsemicarbazide hydrochloride; Semicarbazide, 1-[3-(trifluoromethyl)phenyl]-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[3-(Trifluoromethyl)Phenyl]Semicarbazide Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.