Description

Benzene, 2-Chloro-1-Ethynyl-4-Methoxy- (CAS NO 153440-68-7) is a specialized aromatic building block featuring a unique combination of a chloro, methoxy, and ethynyl substituent on the benzene ring. This compound is valued for its versatility as a key intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactive ethynyl group for molecular diversification.
• Material Science Research: Acts as a monomer or precursor for synthesizing specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel organic reactions and catalytic processes.
• Ligand and Catalyst Preparation: Useful for constructing complex ligand frameworks in coordination chemistry and catalysis development.

Basic Information

Product Name	Benzene, 2-Chloro-1-Ethynyl-4-Methoxy-
CAS No.	153440-68-7
Molecular Formula	C9H7ClO
Molecular Weight	166.60 g/mol
Synonyms	2-Chloro-1-ethynyl-4-methoxybenzene; 1-Chloro-2-ethynyl-5-methoxybenzene; 4-Methoxy-2-chlorophenylacetylene; 2-Chloro-4-methoxyphenylacetylene; 2-Chloro-4-methoxybenzeneacetylene; 2-Chloro-4-methoxyphenylethyne; (2-Chloro-4-methoxyphenyl)ethyne
EINECS	Contact for details

Quality Control

Our Benzene, 2-Chloro-1-Ethynyl-4-Methoxy- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.