Description

L-Proline, 1-Methyl-5-Oxo-, Hydrazide (9Ci) is a high-purity, specialized proline derivative with a reactive hydrazide functional group. This compound is a critical chiral building block and intermediate for the synthesis of complex pharmaceutical agents and bioactive molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific conformational constraints or create novel heterocyclic scaffolds. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of protease inhibitors, antiviral drugs, and other active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used to construct constrained peptide analogs and modify peptide backbones to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the design of novel herbicides and plant growth regulators with specific stereochemical requirements.
• Fine Chemical Production: Employed in asymmetric synthesis and as a ligand or catalyst component in organic transformations.
• Bioconjugation Chemistry: The hydrazide moiety enables selective conjugation with aldehydes and ketones for labeling and linker applications.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and industrial R&D labs.

Basic Information

Product Name	L-Proline, 1-Methyl-5-Oxo-, Hydrazide (9Ci)
CAS No.	153440-30-3
Molecular Formula	C7H13N3O2
Molecular Weight	171.20 g/mol
Synonyms	(2S)-1-Methyl-5-oxopyrrolidine-2-carbohydrazide; L-1-Methyl-5-oxoproline hydrazide; (S)-1-Methyl-5-oxopyrrolidine-2-carboxylic acid hydrazide; 1-Methyl-L-proline 5-lactam hydrazide; 2-Pyrrolidinecarboxylic acid, 1-methyl-5-oxo-, hydrazide, (2S)-; 153440-30-3; Proline, 1-methyl-5-oxo-, hydrazide, L-
EINECS	Contact for details

Quality Control

Our L-Proline, 1-Methyl-5-Oxo-, Hydrazide (9Ci) is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.