Description

n-(3,4-Dichlorophenyl)-6,7-Dimethoxy-4-Quinazolinamine is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinamine class of heterocyclic compounds. This compound is of significant commercial importance due to its critical role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potent kinase inhibitors and other targeted cancer therapies.
• Biochemical Research: Used as a reference standard and a tool compound in pharmacological studies to investigate enzyme inhibition and cellular signaling pathways.
• Drug Discovery & Development: Employed in medicinal chemistry programs for the structure-activity relationship (SAR) optimization of new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Integrated into the final stages of manufacturing processes for specific, high-value active pharmaceutical ingredients.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	n-(3,4-Dichlorophenyl)-6,7-Dimethoxy-4-Quinazolinamine
CAS No.	153437-79-7
Molecular Formula	C₁₆H₁₃Cl₂N₃O₂
Molecular Weight	350.20 g/mol
Synonyms	6,7-Dimethoxy-N-(3,4-dichlorophenyl)quinazolin-4-amine; 4-Quinazolinamine, N-(3,4-dichlorophenyl)-6,7-dimethoxy-; 153437-79-7; N-(3,4-Dichlorophenyl)-6,7-dimethoxyquinazolin-4-amine; 6,7-Dimethoxy-N-(3,4-dichlorophenyl)-4-quinazolinamine
EINECS	Contact for details

Quality Control

Our n-(3,4-Dichlorophenyl)-6,7-Dimethoxy-4-Quinazolinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We can support development projects requiring compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.