Description

Gavestinel is a selective and potent antagonist of the glycine site on the NMDA receptor complex, representing a significant class of neuroprotective agents. This compound is of high interest in advanced pharmaceutical research for its potential to modulate excitatory neurotransmission and mitigate neuronal damage. It is primarily utilized by research institutions and pharmaceutical developers focusing on neurological disorders, stroke, and CNS injury models.

Application

• Neuroscience Research: Used as a critical pharmacological tool to study the role of NMDA receptors and excitotoxicity in cellular and animal models.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of novel neuroprotective therapeutics.
• Preclinical Studies: Employed in experimental models of ischemic stroke, traumatic brain injury, and neurodegenerative conditions to evaluate therapeutic efficacy.
• Biochemical Assays: Acts as a specific ligand in receptor binding studies and high-throughput screening assays to identify new modulators.
• Academic Research: Facilitates fundamental research into glutamate receptor function and synaptic plasticity mechanisms.

Basic Information

Product Name	Gavestinel
CAS No.	153436-38-5
Molecular Formula	C17H16N4O4
Molecular Weight	340.34 g/mol
Synonyms	GV150526; (E)-4,6-Dichloro-3-[(2-oxo-1-phenyl-3-pyrrolidinylidene)methyl]-1H-indole-2-carboxylic acid; GV 150526; 4,6-Dichloro-3-[(E)-[(2-oxo-1-phenyl-3-pyrrolidinylidene)methyl]-1H-indole-2-carboxylic acid; NPC 17742; LY233053
EINECS	Contact for details

Quality Control

Our Gavestinel is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable and reproducible material for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The material should be kept under inert conditions if long-term stability is required. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.