Description

2-Chloro-1-Methylpyridinium Bromide is a versatile and highly reactive organic salt, primarily valued as a powerful coupling agent and catalyst in complex organic synthesis. Its core value proposition lies in its ability to facilitate challenging condensation and esterification reactions with high efficiency and selectivity, making it indispensable for building complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of active pharmaceutical ingredients (APIs), specialty chemicals, and novel polymers.

Application

• Peptide Coupling Reagent: A key reagent for amide bond formation in solid-phase and solution-phase peptide synthesis.
• Esterification & Lactonization Catalyst: Facilitates the formation of esters and lactones from carboxylic acids and alcohols under mild conditions.
• Pharmaceutical Intermediate Synthesis: Used in the multistep synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a catalyst or initiator in the synthesis of specialized polymers and functional materials.
• Academic & Industrial Research: A valuable tool for methodological development and exploratory synthesis in organic chemistry laboratories.
• Chemical Biology Probes: Used in the preparation of labeled compounds and molecular probes for biochemical studies.

Basic Information

Product Name	2-Chloro-1-Methylpyridinium Bromide
CAS No.	153403-89-5
Molecular Formula	C7H9BrClN
Molecular Weight	222.51 g/mol
Synonyms	1-Methyl-2-chloropyridinium Bromide; 2-Chloro-1-methylpyridin-1-ium Bromide; 2-Chloro-N-methylpyridinium Bromide; Mukaiyama's Reagent (Bromide Salt); 1-Methyl-2-chloro-pyridinium Bromide; CMPB; 2-Chloro-1-methylpyridinium Bromide Salt
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Methylpyridinium Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can supply material compliant with various internal quality standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.