Description

.Beta.-D-Glucofuranosiduronic Acid, Methyl 2-(Acetylamino)-2-Deoxy-, .Gamma.-Lactone is a specialized carbohydrate derivative and a key lactonized intermediate in advanced organic synthesis. This compound is valued for its role as a versatile chiral building block, enabling the construction of complex molecular architectures with high stereochemical control. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, bioactive glycoconjugates, and sophisticated chemical probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel glycosidase inhibitors, antiviral agents, and other therapeutic compounds targeting carbohydrate-processing enzymes.
• Glycochemistry Research: Serves as a fundamental building block for constructing complex oligosaccharides, glycopeptides, and glycomimetics for biological activity studies.
• Chemical Biology Probes: Used in the development of activity-based probes and labeled substrates to study enzyme mechanisms and pathways in glycoscience.
• Process Development: Employed in route scouting and optimization for the scalable production of high-value fine chemicals and active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for methodological development in synthetic organic chemistry, particularly in stereoselective synthesis and protecting group strategies.

Basic Information

Product Name	.Beta.-D-Glucofuranosiduronic Acid, Methyl 2-(Acetylamino)-2-Deoxy-, .Gamma.-Lactone
CAS No.	153373-84-3
Molecular Formula	C15H21NO9
Molecular Weight	359.33 g/mol
Synonyms	Methyl 2-acetamido-2-deoxy-β-D-glucofuranosiduronic acid γ-lactone; 2-Acetamido-2-deoxy-β-D-glucofuranosiduronic acid methyl ester γ-lactone; N-Acetyl-β-D-glucosaminuronic acid methyl ester lactone; Methyl (2S,3S,4R,5R)-2-(acetylamino)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carboxylate γ-lactone; GlcNAcA methyl ester lactone; 153373-84-3; β-D-GlcNAcA methyl ester γ-lactone
EINECS	Contact for details

Quality Control

Our production of .Beta.-D-Glucofuranosiduronic Acid, Methyl 2-(Acetylamino)-2-Deoxy-, .Gamma.-Lactone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, including NMR and HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications and can tailor specifications to meet specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.