Description

3-Amino-3-Deoxy-Myo-Inositol 1,4,5-Trisphosphate is a specialized, high-purity biochemical compound that serves as a critical research tool for studying cellular signaling pathways. This molecule is a key analog of inositol trisphosphate (IP3), a vital second messenger involved in calcium release from intracellular stores. It is primarily utilized by researchers and developers in the fields of pharmacology, neurobiology, and cell biology to investigate receptor interactions and signal transduction mechanisms. The compound's unique structure makes it invaluable for probing the intricacies of phosphoinositide metabolism and related therapeutic targets.

Application

• Biochemical Research: As a potent and selective analog of D-myo-Inositol 1,4,5-trisphosphate (IP3) for investigating IP3 receptor binding, activation, and calcium signaling dynamics in cellular systems.
• Pharmacological Studies: Used in high-throughput screening assays and mechanistic studies to identify and characterize novel modulators of the IP3 receptor for potential drug discovery.
• Neuroscience Research: A key tool for studying the role of IP3-mediated calcium signaling in neuronal function, synaptic plasticity, and neurodegenerative disease models.
• Enzyme Inhibition Studies: Serves as a substrate analog or inhibitor for enzymes involved in inositol phosphate metabolism, such as phosphatases and kinases.
• Cell Biology: Used to manipulate intracellular calcium levels experimentally, allowing researchers to study the downstream effects on processes like apoptosis, gene expression, and cell proliferation.
• Diagnostic Development: Potential use as a reference standard or labeled tracer in the development of assays for measuring inositol phosphate levels or receptor activity.

Basic Information

Product Name	3-Amino-3-Deoxy-Myo-Inositol 1,4,5-Trisphosphate
CAS No.	153212-81-8
Molecular Formula	C6H15N1O15P3
Molecular Weight	482.10 g/mol
Synonyms	3-Amino-3-deoxy-D-myo-inositol 1,4,5-trisphosphate; 3-Amino-3-deoxy-myo-inositol 1,4,5-trisphosphate; 3-Amino-3-deoxy-1D-myo-inositol 1,4,5-trisphosphate; 3-Amino-IP3; 3-NH2-IP3; 1D-3-Amino-3-deoxy-myo-inositol 1,4,5-trisphosphate; IP3 analog; Inositol trisphosphate analog
EINECS	Contact for details

Quality Control

Our 3-Amino-3-Deoxy-Myo-Inositol 1,4,5-Trisphosphate is manufactured under strict quality control protocols to ensure the high purity and consistency required for sensitive research applications. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by phosphorus analysis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.