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2-Acetamido-2-Deoxy-4-o-(3-Sulfo-A-D-Galactopyranosyl)-3-o-(A-L-Fucopyranosyl)-D-Glucopyranoside CAS NO 153153-62-9
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CAS No.:153153-62-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Acetamido-2-Deoxy-4-o-(3-Sulfo-A-D-Galactopyranosyl)-3-o-(A-L-Fucopyranosyl)-D-Glucopyranoside is a complex, sulfated oligosaccharide derivative of significant interest in advanced biochemical research and development. This compound matters as a high-purity, structurally defined reference standard for studying carbohydrate-protein interactions, particularly those involving selectins and other lectins. It is primarily needed by research institutions and pharmaceutical companies engaged in glycobiology, inflammation research, and the development of novel therapeutic agents or diagnostic tools.
Application
- Glycobiology Research: Used as a critical reference standard and substrate for studying enzyme kinetics, binding affinities, and the structural biology of carbohydrate-mediated processes.
- Inflammation & Immunology Studies: Serves as a tool compound for investigating selectin-ligand interactions, which are pivotal in leukocyte trafficking and inflammatory responses.
- Pharmaceutical Development: Employed in the screening and development of anti-inflammatory or anti-metastatic drugs that target specific carbohydrate-binding domains.
- Diagnostic Reagent Synthesis: Acts as a key intermediate or hapten in the development of immunoassays and biosensors for detecting specific carbohydrate antigens.
- Enzyme Substrate: Functions as a specific substrate for sulfotransferases, glycosyltransferases, or glycosidases in enzymatic characterization assays.
- Bioconjugation & Probe Development: Utilized for the synthesis of neoglycoconjugates, fluorescent probes, or affinity matrices for pull-down assays and cellular imaging.
Basic Information
| Product Name | 2-Acetamido-2-Deoxy-4-o-(3-Sulfo-A-D-Galactopyranosyl)-3-o-(A-L-Fucopyranosyl)-D-Glucopyranoside |
| CAS No. | 153153-62-9 |
| Molecular Formula | C26H44N2O21S |
| Molecular Weight | 728.70 g/mol |
| Synonyms | 3'-Sulfo Lewis a; Sialyl Lewis X isomer; 3'-Sulfo-Lea; 3'-Sulfo Lacto-N-fucopentaose II; 3'-Sulfo-LNFP II; 3'-Sulfo Lewis a pentasaccharide; 3'-Sulfated Lewis a; 4-O-[3-O-Sulfo-β-D-galactopyranosyl]-3-O-[α-L-fucopyranosyl]-2-acetamido-2-deoxy-D-glucopyranoside |
| EINECS | Contact for details |
Quality Control
Our 2-Acetamido-2-Deoxy-4-o-(3-Sulfo-A-D-Galactopyranosyl)-3-o-(A-L-Fucopyranosyl)-D-Glucopyranoside is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and batch-to-batch consistency suitable for research applications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccation and storage under inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (NMR) | Conforms to structure |
| Identification (MS) | Conforms (M-H)- or (M+Na)+ |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0 % |
| Heavy Metals | < 20 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Biological Activity (Binding Assay) | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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