Description

6,7-Difluoro-2-Methylquinoline is a high-purity fluorinated quinoline derivative, a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile scaffold for developing novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the difluoro-methylquinoline core can enhance biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or charge-transport materials, due to its electron-deficient quinoline structure.
• Chemical Research & Development: Employed as a versatile fluorinated synthon in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Design: Utilized in the preparation of specialized ligands for catalysis, where the nitrogen atom and fluorine substituents can modulate metal-binding properties.

Basic Information

Product Name	6,7-Difluoro-2-Methylquinoline
CAS No.	152922-65-1
Molecular Formula	C₁₀H₇F₂N
Molecular Weight	179.17 g/mol
Synonyms	2-Methyl-6,7-difluoroquinoline; 6,7-Difluoro-2-methylquinoline; Quinoline, 6,7-difluoro-2-methyl-; 2-Methyl-6,7-difluorquinolin; 152922-65-1
EINECS	Contact for details

Quality Control

Our 6,7-Difluoro-2-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.