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N6-(4-Aminobenzyl)-n-Methylcarboxamidoadenosine CAS NO 152918-26-8


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CAS No.:152918-26-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N6-(4-Aminobenzyl)-n-Methylcarboxamidoadenosine is a high-purity, synthetic adenosine derivative designed for advanced research and development applications. This compound serves as a critical biochemical tool for studying adenosine receptor signaling pathways and related cellular mechanisms. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in drug discovery, particularly for cardiovascular, neurological, and inflammatory conditions.

Application

  • Biochemical Research: Used as a reference standard and active ligand in adenosine receptor (AR) binding assays and functional studies.
  • Drug Discovery: Serves as a key intermediate or pharmacophore in the synthesis of novel therapeutic agents targeting A1, A2A, A2B, or A3 adenosine receptors.
  • Enzymology Studies: Employed to investigate the activity and inhibition of enzymes involved in nucleotide metabolism and signaling.
  • Cell Signaling Pathway Analysis: A vital tool for modulating cAMP levels and studying downstream effects in various cell culture models.
  • Academic & Institutional Research: Supports fundamental research in physiology, cardiology, neurobiology, and immunology.
  • Preclinical Development: Used in *in vitro* and *in vivo* studies to evaluate pharmacokinetics, efficacy, and safety profiles of candidate molecules.

Basic Information

Product Name N6-(4-Aminobenzyl)-n-Methylcarboxamidoadenosine
CAS No. 152918-26-8
Molecular Formula C19H24N8O4
Molecular Weight 428.45 g/mol
Synonyms N6-(4-Aminobenzyl)-N-methyl-5'-carboxamidoadenosine; N6-(4-Aminobenzyl)-N-methyl-5'-N-ethylcarboxamidoadenosine (common naming variant); 4-Aminobenzyl-MECA; AB-MECA analog; Adenosine, N6-[(4-aminophenyl)methyl]-N-methyl-5'-carboxamide; N6-(p-Aminobenzyl)-N-methyl-5'-carboxamidoadenosine; A selective adenosine receptor ligand
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Quality Control

Our N6-(4-Aminobenzyl)-n-Methylcarboxamidoadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to maintain stability and prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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