Description

1,1,3,3-Tetramethoxycyclobutane is a versatile, highly volatile chemical intermediate featuring a unique cyclobutane ring structure with four methoxy substituents. This compound is valued for its role as a key building block in advanced organic synthesis, enabling the creation of complex molecular architectures. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for applications requiring precise, high-purity intermediates.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive methoxy groups.
• Polymer & Material Science: Acts as a cross-linking agent or monomer in the production of specialty polymers, resins, and high-performance materials.
• Organic Synthesis Reagent: Employed in research laboratories for cycloaddition reactions, ring-opening polymerizations, and as a protected diol equivalent.
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing specific aroma chemicals and odorants.
• Electrolyte Additive Research: Investigated for use in advanced battery formulations due to its unique cyclic ether structure.

Basic Information

Product Name	1,1,3,3-Tetramethoxycyclobutane
CAS No.	152897-19-3
Molecular Formula	C8H16O4
Molecular Weight	176.21 g/mol
Synonyms	Cyclobutane-1,1,3,3-tetrayl tetramethanoate; 1,1,3,3-Tetramethoxy-cyclobutane; Tetramethoxycyclobutane; Cyclobutane-1,1,3,3-tetrol tetramethyl ether; 1,1,3,3-Tetramethyl cyclobutane-1,1,3,3-tetracarboxylate (common misnomer); TMCB (abbreviation); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1,1,3,3-Tetramethoxycyclobutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Gravity (20°C)	1.020 - 1.050
Refractive Index (n20D)	1.430 - 1.450

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.