Description

2-Benzyloxycarbonylamino-Nicotinic Acid is a high-purity, protected nicotinic acid derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile, protected amino-nicotinic acid scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within the fields of oncology, neurology, and metabolic disease.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Chemistry: Used to incorporate nicotinic acid motifs into peptide-like structures for drug discovery.
• Ligand Synthesis: Building block for creating novel ligands in catalyst development and metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate in the development of new herbicides and plant growth regulators.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and probes for biochemical studies.
• Academic & Contract Research: Serves as a specialized reagent for method development and novel synthetic route exploration in R&D laboratories.

Basic Information

Product Name	2-Benzyloxycarbonylamino-Nicotinic Acid
CAS No.	152666-98-3
Molecular Formula	C14H12N2O4
Molecular Weight	272.26 g/mol
Synonyms	2-[(Benzyloxy)carbonylamino]nicotinic acid; 2-(N-Cbz-amino)nicotinic acid; 2-(Benzyloxycarbonylamino)pyridine-3-carboxylic acid; Cbz-Amino Nicotinic Acid; Z-Amino Nicotinic Acid; 2-Carboxy-3-pyridinylcarbamic acid benzyl ester; 3-Pyridinecarboxylic acid, 2-[[(phenylmethoxy)carbonyl]amino]-; 2-(Benzyloxycarbonylamino)-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Benzyloxycarbonylamino-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, ensuring compliance with the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for chemicals soluble in strong acid/organic solvent. Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.