Description

6-Acetylmorphine-D6 is a stable isotope-labeled analog of 6-acetylmorphine, a primary metabolite of heroin. This compound is of critical importance for use as an internal standard in analytical chemistry, ensuring the accuracy and reliability of quantitative measurements. It is primarily needed by forensic, clinical, and pharmaceutical research laboratories for applications in drug testing, pharmacokinetic studies, and method development.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for precise quantification of 6-acetylmorphine and related opiates in LC-MS/MS and GC-MS analysis.
• Forensic Toxicology: Used in the confirmation and quantification of heroin use in biological matrices such as urine, blood, and hair.
• Clinical Research: Supports studies on drug metabolism, pharmacokinetics, and the development of diagnostic assays for substance abuse.
• Pharmaceutical Analysis: Aids in impurity profiling, stability testing, and method validation for controlled substance analysis.
• Reference Material: Serves as a certified reference material (CRM) for calibrating laboratory equipment and ensuring regulatory compliance.
• Metabolite Studies: Facilitates research into the metabolic pathways and biological fate of heroin and its derivatives.

Basic Information

Product Name	6-Acetylmorphine-D6
CAS No.	152477-90-2
Molecular Formula	C19H15D6NO4
Molecular Weight	327.38 g/mol
Synonyms	6-Monoacetylmorphine-D6; 6-MAM-D6; 6-Acetyl-17-methyl-4,5α-epoxy-7,8-didehydromorphinan-3,6α-diol-3-acetate-D6; Heroin Metabolite-D6; (5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol 6-acetate-D6; 6-Acetylmorphine-d6; 6-AM-D6
EINECS	Contact for details

Quality Control

Our 6-Acetylmorphine-D6 is produced under strict quality management systems to ensure the highest standards of purity and isotopic enrichment required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing chemical purity, isotopic purity (D-enrichment), and chromatographic data is provided to guarantee traceability and compliance with your research or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.