Description

2-(Quinolin-8-Yl)Acetic Acid is a versatile quinoline derivative that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique structure, featuring both a quinoline heterocycle and a reactive acetic acid side chain, makes it valuable for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications ranging from ligand synthesis to the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Ligand Synthesis: Used to prepare chelating ligands for catalysis and metal-organic frameworks (MOFs), leveraging the coordinating ability of the quinoline nitrogen.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the synthesis of organic semiconductors, fluorescent dyes, and photoactive compounds due to the quinoline scaffold's photophysical properties.
• Chemical Biology: Useful for creating molecular probes and bioconjugates to study biological processes.
• Academic & Industrial R&D: A fundamental reagent for method development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-(Quinolin-8-Yl)Acetic Acid
CAS No.	152150-04-4
Molecular Formula	C₁₁H₉NO₂
Molecular Weight	187.20 g/mol
Synonyms	8-Quinolineacetic Acid; (8-Quinolyl)acetic Acid; 2-(8-Quinolyl)acetic Acid; Quinolin-8-yl-acetic acid; 8-Quinolinylacetic Acid; 2-Quinolin-8-yl-acetic acid; 2-(8-Quinolinyl)acetic Acid; NSC 339586
EINECS	Contact for details

Quality Control

Our production of 2-(Quinolin-8-Yl)Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and FTIR, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP-compliant manufacturing for advanced applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices for strong acids/organic solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.