Description

Methyl 5-o-tert-Butyldiphenylsilyl-2-Deoxy-3-o-(4-Methylbenzenesulfonyl)-D-Erythro-Pentofuranoside is a sophisticated, high-purity nucleoside derivative and a critical protected intermediate in synthetic organic chemistry. Its value lies in enabling precise, multi-step synthesis of complex molecules, particularly in the development of novel pharmaceuticals and bioactive compounds. This product is essential for researchers and manufacturers in pharmaceutical R&D, nucleoside chemistry, and fine chemical synthesis who require reliable, high-quality building blocks for advanced projects.

Application

• Pharmaceutical Intermediate: A key protected building block in the multi-step synthesis of antiviral and anticancer nucleoside analogs.
• Nucleoside Chemistry Research: Used in academic and industrial laboratories for studying glycosylation reactions and developing new synthetic methodologies.
• Oligonucleotide Synthesis: Serves as a precursor for modified nucleosides used in the creation of antisense oligonucleotides and siRNA therapeutics.
• Prodrug Development: Employed in the design and synthesis of prodrugs to enhance the bioavailability and targeting of active pharmaceutical ingredients (APIs).
• Fine Chemical Manufacturing: Acts as a specialized intermediate for producing high-value, complex organic molecules with specific stereochemical configurations.

Basic Information

Product Name	Methyl 5-o-tert-Butyldiphenylsilyl-2-Deoxy-3-o-(4-Methylbenzenesulfonyl)-D-Erythro-Pentofuranoside
CAS No.	152039-44-6
Molecular Formula	C30H38O6SSi
Molecular Weight	554.78 g/mol
Synonyms	Methyl 5-O-(tert-Butyldiphenylsilyl)-2-deoxy-3-O-(p-toluenesulfonyl)-D-erythro-pentofuranoside; 1-[(2R,3R,5R)-5-[[tert-Butyl(diphenyl)silyl]oxymethyl]-3-[(4-methylphenyl)sulfonyl]oxyoxolan-2-yl]methoxy-methane; Methyl 3-O-tosyl-5-O-TBDPS-2-deoxy-D-ribofuranoside; 2-Deoxy-3-O-tosyl-5-O-TBDPS-D-ribofuranoside methyl ether; TBDPS-protected 2-deoxy-3-O-tosyl ribofuranoside methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-o-tert-Butyldiphenylsilyl-2-Deoxy-3-o-(4-Methylbenzenesulfonyl)-D-Erythro-Pentofuranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.