Description

5(3H)-Indolizinone,6,8A-Dihydro-,(R)-(9Ci) is a chiral, non-racemic indolizinone derivative, a valuable synthetic intermediate in advanced organic chemistry. This compound matters for its role as a key building block in the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials. The product is supplied with a CAS registry number of 151983-37-8.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, particularly in classes targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Synthesis: Used in the construction of complex, biologically active molecules for novel pesticides and herbicides, leveraging its unique fused-ring structure.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances where high stereochemical purity is required.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental studies in heterocyclic chemistry and synthetic organic chemistry.

Basic Information

Item	Details
Product Name	5(3H)-Indolizinone,6,8A-Dihydro-,(R)-(9Ci)
CAS No.	151983-37-8
Molecular Formula	C8H9NO
Molecular Weight	135.16 g/mol
Synonyms	(R)-6,8a-Dihydro-5(3H)-indolizinone; (R)-1-Azabicyclo[3.3.0]oct-2-en-3-one; (R)-Octahydroindolizin-3-one; (R)-Indolizinone derivative; 151983-37-8; (R)-Dihydroindolizinone; (R)-3-Oxo-1-azabicyclo[3.3.0]oct-2-ene
EINECS	Contact for details

Quality Control

Every batch of our 5(3H)-Indolizinone,6,8A-Dihydro-,(R)-(9Ci) is produced and tested under a strict quality management system. We ensure high chiral purity and chemical integrity through advanced analytical techniques including chiral HPLC, NMR, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.