Description

Pyrido[1,2-A]Indole-8-Carboxylic Acid, 6,7,8,9-Tetrahydro-9-Oxo-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the production of active pharmaceutical ingredients, especially those containing fused pyridoindole core structures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Biochemical Reagent: Potential use as a specialized reagent or inhibitor in biochemical and pharmacological assays.

Basic Information

Product Name	Pyrido[1,2-A]Indole-8-Carboxylic Acid, 6,7,8,9-Tetrahydro-9-Oxo-, Ethyl Ester
CAS No.	151825-54-6
Molecular Formula	C16H15NO3
Molecular Weight	269.30 g/mol
Synonyms	Ethyl 9-oxo-6,7,8,9-tetrahydropyrido[1,2-a]indole-8-carboxylate; 8-Carbethoxy-6,7,8,9-tetrahydropyrido[1,2-a]indol-9-one; 6,7,8,9-Tetrahydropyrido[1,2-a]indole-9-one-8-carboxylic acid ethyl ester; Ethyl 6,7,8,9-tetrahydropyrido[1,2-a]indole-9-one-8-carboxylate; 8-Ethoxycarbonyl-6,7,8,9-tetrahydropyrido[1,2-a]indol-9-one; Pyrido[1,2-a]indole-8-carboxylic acid, 6,7,8,9-tetrahydro-9-oxo-, ethyl ester; CAS 151825-54-6
EINECS	Contact for details

Quality Control

Our production of Pyrido[1,2-A]Indole-8-Carboxylic Acid, 6,7,8,9-Tetrahydro-9-Oxo-, Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identification by spectroscopic methods, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.