Description

Trifluoromethanesulfonic Acid 6-Bromo-2-Naphthyl Ester is a specialized organofluorine building block and a reactive triflate ester derivative. This compound is valued for its role as a versatile electrophile in cross-coupling reactions, enabling the efficient synthesis of complex naphthalene-based structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecules and intermediates.

Application

• Pharmaceutical Intermediate: A key electrophile in Suzuki, Stille, and Negishi cross-coupling reactions for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate functionalized naphthalene scaffolds.
• Material Science Research: Serves as a precursor for creating organic semiconductors, liquid crystals, and fluorescent dyes through palladium-catalyzed coupling.
• Organic Synthesis: An effective reagent for introducing the 6-bromo-2-naphthyl moiety into complex molecular architectures under mild conditions.
• Catalyst & Ligand Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	Trifluoromethanesulfonic Acid 6-Bromo-2-Naphthyl Ester
CAS No.	151600-02-1
Molecular Formula	C₁₂H₆BrF₃O₃S
Molecular Weight	367.14 g/mol
Synonyms	6-Bromo-2-naphthyl trifluoromethanesulfonate; 6-Bromo-2-naphthyl triflate; 6-Bromo-2-naphthalenyl trifluoromethanesulfonate; 2-Naphthyl triflate, 6-bromo-; Trifluoromethanesulfonic acid 6-bromo-2-naphthalenyl ester; 6-Br-2-NaphOTf
EINECS	Contact for details

Quality Control

Our Trifluoromethanesulfonic Acid 6-Bromo-2-Naphthyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.