Description

(1S)-6,6'-Dimethoxy[1,1'-Biphenyl]-2,2'-Diamine is a high-purity chiral biphenyl diamine derivative, identified by CAS number 151489-85-9. This compound serves as a critical chiral building block and ligand precursor in advanced organic synthesis, valued for its structural rigidity and defined stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing enantiomerically pure active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalysis: Used as a starting material for synthesizing chiral ligands and catalysts for enantioselective transformations, such as hydrogenations and cross-couplings.
• Agrochemical Synthesis: Employed in the research and development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialized polymers, liquid crystals, and advanced organic frameworks (MOFs/COFs).
• Analytical Standard: Serves as a high-purity reference standard for analytical method development and quality control in chiral separation techniques (e.g., HPLC, SFC).

Basic Information

Product Name	(1S)-6,6'-Dimethoxy[1,1'-Biphenyl]-2,2'-Diamine
CAS No.	151489-85-9
Molecular Formula	C14H16N2O2
Molecular Weight	244.29 g/mol
Synonyms	(S)-6,6'-Dimethoxybiphenyl-2,2'-diamine; (1S)-6,6'-Dimethoxy-2,2'-diaminobiphenyl; (S)-2,2'-Diamino-6,6'-dimethoxy-1,1'-biphenyl; (S)-DADMBP; (S)-(-)-6,6'-Dimethoxy-2,2'-diaminobiphenyl; BINAM derivative; Chiral biphenyl diamine
EINECS	Contact for details

Quality Control

Our (1S)-6,6'-Dimethoxy[1,1'-Biphenyl]-2,2'-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), chemical purity (HPLC), and identity confirmation (IR, NMR) to ensure it meets stringent specifications for research and production use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flame, and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.