Description

.Alpha.-L-Tagatofuranose, 1,2:4,6-Bis-o-(1-Methylethylidene)- is a high-purity, protected sugar derivative, specifically a diacetonide of L-tagatose. This compound is a crucial chiral intermediate and building block in organic synthesis, offering a locked furanose ring structure for stereoselective transformations. It is primarily required by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, carbohydrate-based drugs, and complex natural products.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Carbohydrate Chemistry: Used as a protected starting material for the preparation of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Asymmetric Synthesis: Acts as a chiral pool reagent or auxiliary for constructing stereogenic centers in medicinal chemistry and natural product synthesis.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor for glycosidases and glycosyltransferases.
• Fine Chemical Production: Utilized in the scaled-up manufacture of specialty chemicals where a specific, protected sugar framework is required.

Basic Information

Product Name	.Alpha.-L-Tagatofuranose, 1,2:4,6-Bis-o-(1-Methylethylidene)-
CAS No.	151377-79-6
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	1,2:4,6-Di-O-isopropylidene-α-L-tagatofuranose; α-L-Tagatofuranose diacetonide; 1,2:4,6-Di-O-(1-methylethylidene)-α-L-tagatofuranose; L-Tagatose 1,2:4,6-di-O-isopropylidene acetal; Di-O-isopropylidene-L-tagatofuranose; Protected L-tagatose
EINECS	Contact for details

Quality Control

Our .Alpha.-L-Tagatofuranose, 1,2:4,6-Bis-o-(1-Methylethylidene)- is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), chiral purity, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.