Description

H-3,5-Diiodo-Tyr-Ome Hcl is a chemically modified, iodinated tyrosine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in the development of novel pharmaceuticals and biochemical probes, particularly in thyroid hormone research and radiopharmaceutical precursor chemistry. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in peptide modification, tracer development, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thyroid hormone analogs and related therapeutic agents.
• Biochemical Research: Used as a labeled compound or a blocking agent in metabolic pathway studies and enzyme inhibition assays.
• Peptide Chemistry: Serves as a modified amino acid building block for introducing iodine atoms into synthetic peptides for structure-activity relationship (SAR) studies.
• Radiopharmaceuticals: Potential precursor for the development of iodine-123 or iodine-131 labeled diagnostic or therapeutic agents.
• Organic Synthesis: Valuable intermediate for constructing complex molecules requiring diiodophenol or protected iodotyrosine motifs.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	H-3,5-Diiodo-Tyr-Ome Hcl
CAS No.	151266-48-7
Molecular Formula	C10H11I2NO3 • HCl
Molecular Weight	516.47 g/mol
Synonyms	3,5-Diiodo-O-methyl-L-tyrosine Hydrochloride; O-Methyl-3,5-diiodo-L-tyrosine Hydrochloride; H-Diiodotyrosine(OMe)-OH HCl; Methyl 2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoate Hydrochloride; L-Tyrosine, O-methyl-3,5-diiodo-, hydrochloride; 3,5-Diiodo-O-methyltyrosine HCl; (2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our H-3,5-Diiodo-Tyr-Ome Hcl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.