Description

2-Chloro-7,8-Dihydro-7,8-Dihydroxyquinoline is a specialized quinoline derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and intermediate for developing complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological or infectious diseases.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and herbicides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and asymmetric synthesis research.

Basic Information

Product Name	2-Chloro-7,8-Dihydro-7,8-Dihydroxyquinoline
CAS No.	151262-67-8
Molecular Formula	C9H8ClNO2
Molecular Weight	197.62 g/mol
Synonyms	2-Chloro-7,8-dihydroxy-7,8-dihydroquinoline; 2-Chloro-7,8-dihydro-7,8-dihydroxyquinoline; 7,8-Dihydro-7,8-dihydroxy-2-chloroquinoline; 2-Chloro-7,8-dihydroxy-1,2,3,4-tetrahydroquinoline; (7R,8S)-2-Chloro-7,8-dihydroxy-7,8-dihydroquinoline (enantiomer); (7S,8R)-2-Chloro-7,8-dihydroxy-7,8-dihydroquinoline (enantiomer); 2-Chlorotetrahydro-7,8-dihydroxyquinoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-7,8-Dihydro-7,8-Dihydroxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grades)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.