Description

1-(4-Bromophenyl)Cyclobutanecarboxylic Acid is a versatile brominated cyclobutane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and an aromatic bromine moiety, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the bromophenyl group can be leveraged for further functionalization.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Building block for synthesizing monomers and polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and protein interactions.
• Academic & R&D: Fundamental research compound for methodological studies in organic chemistry, including cross-coupling reactions and ring-expansion chemistry.

Basic Information

Product Name	1-(4-Bromophenyl)Cyclobutanecarboxylic Acid
CAS No.	151157-49-2
Molecular Formula	C11H11BrO2
Molecular Weight	255.11 g/mol
Synonyms	4-Bromo-α-phenylcyclobutanemethanol carboxylic acid; 1-(p-Bromophenyl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-(4-bromophenyl)-; 1-(4-Bromophenyl)cyclobutane-1-carboxylic acid; p-Bromophenylcyclobutanecarboxylic acid; 4-Bromophenyl cyclobutanecarboxylate (precursor form); BPCBA (abbreviation).
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromophenyl)Cyclobutanecarboxylic Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.