Description

(S)-4-[2-[Bis(Cyclohexylamino)Methyleneamino]-3-(2-Naphthalenyl)-1-Oxopropylamino]Benzyl Tributyl Phosphonium Chloride Hydrochloride is a high-purity, chiral phosphonium salt compound designed for advanced chemical synthesis and research applications. Its complex structure makes it a valuable reagent for facilitating challenging transformations, particularly in the development of pharmaceuticals and specialty chemicals. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise, high-quality building blocks for complex molecule assembly.

Application

• As a phase-transfer catalyst (PTC) in organic synthesis, enabling reactions between reagents in immiscible phases.
• A key chiral intermediate or catalyst in the asymmetric synthesis of active pharmaceutical ingredients (APIs).
• Utilized in peptide coupling and amide bond formation reactions due to its phosphonium structure.
• Employed in academic and industrial R&D for developing novel synthetic methodologies.
• Potential use in the synthesis of specialty polymers and advanced materials with specific functional properties.
• Serves as a precursor or ligand for the preparation of other organometallic or catalytic complexes.

Basic Information

Product Name	(S)-4-[2-[Bis(Cyclohexylamino)Methyleneamino]-3-(2-Naphthalenyl)-1-Oxopropylamino]Benzyl Tributyl Phosphonium Chloride Hydrochloride
CAS No.	151039-63-3
Molecular Formula	C43H62ClN4OP • HCl
Molecular Weight	~770.37 g/mol (Free base)
Synonyms	(S)-4-[(2-{[Bis(cyclohexylamino)methylene]amino}-3-(naphthalen-2-yl)-1-oxopropyl)amino]benzyl tributylphosphonium chloride hydrochloride; (S)-Benzyltributylphosphonium chloride derivative; (S)-ATPHC; (S)-Chiral Phosphonium Salt 151039-63-3; (S)-PTC Reagent 151039-63-3; (S)-4-(N-{2-[(Bis-cyclohexylamino-methylene)-amino]-3-naphthalen-2-yl-propionyl}-amino)-benzyl-tributyl-phosphonium chloride hydrochloride; Benzyltributylphosphonium chloride, 4-[[(2S)-2-[[[bis(cyclohexylamino)methylene]amino]-3-(2-naphthalenyl)-1-oxopropyl]amino]-, hydrochloride (1:?)
EINECS	Contact for details

Quality Control

Our production of (S)-4-[2-[Bis(Cyclohexylamino)Methyleneamino]-3-(2-Naphthalenyl)-1-Oxopropylamino]Benzyl Tributyl Phosphonium Chloride Hydrochloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC for assay and chiral purity, NMR for structural confirmation, and tests for residual solvents and moisture. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.