Description

Rac 4-Hydroxy-9-cis-Retinoic Acid is a synthetic retinoid derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound is valued for its role as a key intermediate and reference standard in studying retinoid signaling pathways and metabolism. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics targeting dermatological conditions, oncology, and cellular differentiation processes.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and biochemical tool for investigating retinoid receptor (RAR/RXR) activity and metabolic pathways.
• Dermatology Drug Discovery: Used in preclinical studies for developing new treatments for skin disorders such as acne, psoriasis, and photoaging.
• Oncology Research: Employed in cellular studies to explore the effects of retinoids on cell proliferation, differentiation, and apoptosis in various cancer models.
• Metabolic Studies: Acts as a substrate or intermediate in enzymatic studies to understand the biosynthesis and catabolism of vitamin A derivatives.
• Analytical Standard: Provides a high-purity standard for method development and quality control in HPLC, LC-MS, and other analytical techniques within QC laboratories.

Basic Information

Product Name	Rac 4-Hydroxy-9-cis-Retinoic Acid
CAS No.	150737-17-0
Molecular Formula	C₂₀H₂₈O₃
Molecular Weight	316.44 g/mol
Synonyms	(9Z)-4-Hydroxyretinoic Acid; 4-Hydroxy-9-cis-retinoic Acid; 9-cis-4-Hydroxyretinoic Acid; all-rac-4-Hydroxy-9-cis-retinoic Acid; (±)-4-Hydroxy-9-cis-retinoic Acid; 9Z-4-OH-RA; 4-OH-9C-RA; Vitamin A Acid Derivative
EINECS	Contact for details

Quality Control

Our Rac 4-Hydroxy-9-cis-Retinoic Acid is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.