Description

4-Acetoxybutyric Anhydride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its bifunctional structure, containing both an anhydride and an ester group, makes it a versatile building block for the controlled introduction of the 4-acetoxybutyryl moiety. This compound is essential for research chemists and process development scientists working in the pharmaceutical and fine chemical industries, where it is used to create novel active pharmaceutical ingredients (APIs) and complex specialty molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly for introducing functionalized side chains.
• Polymer Chemistry: Used as a monomer or co-monomer in the production of specialty polyesters and polyanhydrides with tailored degradation profiles.
• Fine Chemical Synthesis: Serves as a versatile acylating agent and linker in multi-step organic syntheses for research and development.
• Bioconjugation: Potential application in modifying biomolecules, peptides, or polymers through its reactive anhydride group.
• Material Science: Intermediate for creating surface modifiers, coatings, or cross-linking agents with specific chemical functionalities.
• Chemical Research: Valuable reagent for academic and industrial R&D exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	4-Acetoxybutyric Anhydride
CAS No.	150620-32-9
Molecular Formula	C12H18O7
Molecular Weight	274.27 g/mol
Synonyms	Butanoic acid, 4-(acetyloxy)-, anhydride; 4-Acetoxybutanoic anhydride; 4-(Acetyloxy)butyric anhydride; Acetic acid 4-(1-oxobutoxy)butyl ester; γ-Acetoxybutyric anhydride
EINECS	Contact for details

Quality Control

Our 4-Acetoxybutyric Anhydride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, water content, and related substances is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent hydrolysis. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.