Description

2-Amino-2-Cyclohexylacetonitrile Hydrochloride is a versatile chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its ability to introduce a functionalized cyclohexyl moiety, which is a key structural feature in many bioactive molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral drugs, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific stereochemistry for efficacy.
• Chiral Ligand & Catalyst Development: Serves as a starting material for creating novel chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and conformationally restricted amino acid derivatives for medicinal chemistry.
• Fine Chemical Production: A key building block for custom synthesis and the manufacture of specialty chemicals with high purity requirements.

Basic Information

Product Name	2-Amino-2-Cyclohexylacetonitrile Hydrochloride
CAS No.	150512-61-1
Molecular Formula	C8H14N2·HCl
Molecular Weight	174.67 g/mol
Synonyms	2-Cyclohexylglycinonitrile Hydrochloride; (Aminocyclohexyl)acetonitrile Hydrochloride; 2-Amino-2-cyclohexylethanenitrile Hydrochloride; α-Aminocyclohexaneacetonitrile Hydrochloride; 2-Cyclohexyl-2-aminoacetonitrile HCl; Amino(cyclohexyl)acetonitrile Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-Cyclohexylacetonitrile Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, chiral purity analysis, and residual solvent testing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.