Description

4-Oxo-3,4-Dihydro-Quinazoline-6-Carboxylic Acid Amide is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is essential for research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for drug discovery and production.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel quinazolinone-based drug candidates.
• Kinase Inhibitor Synthesis: Core scaffold in the research and production of small molecule kinase inhibitors for oncology and inflammatory diseases.
• API Manufacturing: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring the quinazolinone pharmacophore.
• Biochemical Research: Serves as a standard or reference compound in enzymatic assays and structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Building block for creating specialized compounds used in agrochemical and material science research.

Basic Information

Product Name	4-Oxo-3,4-Dihydro-Quinazoline-6-Carboxylic Acid Amide
CAS No.	150454-06-1
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	6-Carbamoyl-3,4-dihydro-4-oxoquinazoline; 4-Oxo-3,4-dihydroquinazoline-6-carboxamide; Quinazolin-4(3H)-one-6-carboxamide; 6-Aminocarbonyl-4(3H)-quinazolinone; 150454-06-1; 4-Oxo-3,4-dihydroquinazoline-6-carboxylic acid amide
EINECS	Contact for details

Quality Control

Every batch of 4-Oxo-3,4-Dihydro-Quinazoline-6-Carboxylic Acid Amide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.