Description

4-((3,4-(Methylenedioxy)Benzyl)Amino)-6,7,8-Trimethoxyquinazoline is a high-purity, synthetically derived quinazoline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and key intermediate for the synthesis of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation small molecule inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel tyrosine kinase inhibitors (TKIs) and other targeted cancer therapies.
• Biochemical Research: Used as a reference standard or active scaffold in structure-activity relationship (SAR) studies and high-throughput screening (HTS) campaigns.
• Academic Research: Employed in medicinal chemistry programs investigating quinazoline-based compounds for various biological targets.
• API Development: Serves as a critical intermediate in the development and scale-up of new active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in bespoke, complex organic molecules.

Basic Information

Product Name	4-((3,4-(Methylenedioxy)Benzyl)Amino)-6,7,8-Trimethoxyquinazoline
CAS No.	150450-00-3
Molecular Formula	C21H21N3O5
Molecular Weight	395.41 g/mol
Synonyms	6,7,8-Trimethoxy-4-[(3,4-methylenedioxybenzyl)amino]quinazoline; 4-[(3,4-Methylenedioxybenzyl)amino]-6,7,8-trimethoxyquinazoline; 4-(3,4-Methylenedioxybenzylamino)-6,7,8-trimethoxyquinazoline; 4-((3,4-(Methylenedioxy)benzyl)amino)-6,7,8-trimethoxyquinazoline; 150450-00-3; Quinazoline, 4-[(3,4-(methylenedioxy)benzyl)amino]-6,7,8-trimethoxy-
EINECS	Contact for details

Quality Control

Our 4-((3,4-(Methylenedioxy)Benzyl)Amino)-6,7,8-Trimethoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.