Description

2,4-Dichloroquinazoline-6-Carbonitrile is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual reactive sites, the chlorines and the nitrile group, which allow for selective and sequential functionalization to create complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring complex, functionalized quinazoline cores.
• Academic & Institutional Research: Utilized in medicinal chemistry programs and methodology development for C-N and C-C cross-coupling reactions.

Basic Information

Product Name	2,4-Dichloroquinazoline-6-Carbonitrile
CAS No.	150449-98-2
Molecular Formula	C9H3Cl2N3
Molecular Weight	224.05 g/mol
Synonyms	6-Cyano-2,4-dichloroquinazoline; 2,4-Dichloro-6-quinazolinecarbonitrile; 2,4-Dichloro-6-cyanoquinazoline; Quinazoline-6-carbonitrile, 2,4-dichloro-; 150449-98-2; 2,4-Dichlor-6-cyanchinazolin (German); 2,4-ジクロロ-6-シアノキナゾリン (Japanese)
EINECS	Contact for details

Quality Control

Our 2,4-Dichloroquinazoline-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.