Description

4-Chloroquinazoline-6-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its dual reactive sites—the chlorinated position and the nitrile group—which enable efficient derivatization into complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used to build novel herbicide and fungicide candidates with specific modes of action.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Synthesis: Acts as a versatile scaffold for constructing complex quinazoline-based libraries for high-throughput screening.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	4-Chloroquinazoline-6-Carbonitrile
CAS No.	150449-97-1
Molecular Formula	C9H4ClN3
Molecular Weight	189.60 g/mol
Synonyms	6-Cyano-4-chloroquinazoline; 4-Chloro-6-cyanoquinazoline; 4-Chloro-6-quinazolinecarbonitrile; Quinazoline-6-carbonitrile, 4-chloro-; 150449-97-1; 4-Chlor-6-cyanochinazolin (German); 4-Cloro-6-cianochinazolina (Italian)
EINECS	Contact for details

Quality Control

Every batch of 4-Chloroquinazoline-6-Carbonitrile is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.