Description

Ethyl 4-Chloro-6,8-Difluoroquinoline-3-Carboxylate is a high-purity fluorinated quinoline derivative, a critical advanced intermediate in modern organic synthesis. Its value lies in its versatile halogenated and ester-functionalized structure, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel quinolone and fluoroquinolone-based drug candidates with potential antibacterial, anticancer, or antiviral activity.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the difluoroquinoline core can contribute to enhanced biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the development of functional organic materials, such as ligands for catalysts or components for organic electronic devices.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for client projects.

Basic Information

Product Name	Ethyl 4-Chloro-6,8-Difluoroquinoline-3-Carboxylate
CAS No.	150258-20-1
Molecular Formula	C₁₂H₈ClF₂NO₂
Molecular Weight	271.65 g/mol
Synonyms	Ethyl 4-chloro-6,8-difluoroquinoline-3-carboxylate; 4-Chloro-6,8-difluoroquinoline-3-carboxylic acid ethyl ester; 6,8-Difluoro-4-chloroquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-chloro-6,8-difluoro-, ethyl ester; Ethyl 4-chloro-6,8-difluoro-3-quinolinecarboxylate; 150258-20-1; CAS 150258-20-1
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-6,8-Difluoroquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and scale-up activities with reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.