Description

n-(9H-Fluoren-9-Ylethoxycarbonyl)-4-Aminobenzoic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled, sequential assembly of complex peptides by protecting the amine group during coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and novel biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated, stepwise construction of custom peptide sequences.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Combinatorial Chemistry: A valuable reagent in libraries for high-throughput screening of bioactive compounds.
• Proteomics & Biochemical Research: Employed in the study of protein-protein interactions and the synthesis of peptide probes or standards.
• Material Science: Potential use in creating peptide-functionalized surfaces or bio-inspired polymers.

Basic Information

Product Name	n-(9H-Fluoren-9-Ylethoxycarbonyl)-4-Aminobenzoic Acid
CAS No.	150256-47-6
Molecular Formula	C23H19NO4
Molecular Weight	373.40 g/mol
Synonyms	Fmoc-4-Abz-OH; Fmoc-4-Aminobenzoic Acid; 4-[(9H-Fluoren-9-ylmethoxy)carbonyl]aminobenzoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-aminobenzoic Acid; N-Fmoc-4-aminobenzoic Acid; 4-(Fmoc-amino)benzoic Acid; Fmoc-p-aminobenzoic Acid; N-[(9-Fluorenylmethoxy)carbonyl]-4-aminobenzoic Acid
EINECS	Contact for details

Quality Control

Our n-(9H-Fluoren-9-Ylethoxycarbonyl)-4-Aminobenzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.