Description

S-(-)-2,2-Dibromo-1,1'-Binaphthyl CAS NO 150024-49-0 is a high-purity, chiral binaphthyl derivative characterized by its specific stereochemistry and bromine substitution. This compound is a critical chiral building block and ligand precursor in advanced organic synthesis and asymmetric catalysis. It is primarily utilized by pharmaceutical R&D, fine chemical manufacturers, and academic research institutions for developing novel active ingredients and catalytic systems.

Application

• Chiral Ligand Synthesis: A key precursor for synthesizing sophisticated chiral phosphine and N-heterocyclic carbene (NHC) ligands used in asymmetric hydrogenation and cross-coupling reactions.
• Pharmaceutical Intermediates: Serves as a vital scaffold in the research and development of enantiomerically pure drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Asymmetric Catalysis: Employed in the preparation of catalysts for creating chiral centers with high enantiomeric excess (ee) in fine chemical and agrochemical production.
• Material Science Research: Used in the development of chiral organic materials, such as liquid crystals and polymers with specific optical properties.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry and for scaling up asymmetric synthetic routes.

Basic Information

Product Name	S-(-)-2,2-Dibromo-1,1'-Binaphthyl
CAS No.	150024-49-0
Molecular Formula	C₂₀H₁₂Br₂
Molecular Weight	412.12 g/mol
Synonyms	(S)-2,2'-Dibromo-1,1'-binaphthyl; (S)-(-)-2,2'-Dibromo-1,1'-binaphthyl; (S)-2,2'-Dibromobinaphthyl; S-BINOL-Br₂; (S)-2,2'-Dibromo[1,1'-binaphthalene]-2,2'-diol (precursor name); 1,1'-Binaphthalene, 2,2'-dibromo-, (S)-; S-(-)-2,2'-Dibromobinaphthyl
EINECS	Contact for details

Quality Control

Our S-(-)-2,2-Dibromo-1,1'-Binaphthyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.