Description

O(1),O(3)-Bis(Ethoxycarbonylmethyl)-O(2),O(4)-Dimethyl-p-tert-Butylcalix[4]Arene is a strategically functionalized calixarene derivative, a key building block in supramolecular chemistry and advanced material science. Its value lies in its precisely engineered lower-rim ester and ether groups, which create a versatile molecular scaffold for constructing selective receptors, catalysts, and nano-structured materials. This compound is essential for researchers and manufacturers in pharmaceutical development, chemical sensing, and separation technologies who require high-purity, structurally defined host molecules.

Application

• Ion-Selective Receptors & Sensors: Acts as a key precursor for developing selective ionophores for potentiometric sensors targeting alkali and alkaline earth metal ions.
• Catalyst & Ligand Design: Serves as a versatile platform for synthesizing tailored ligands for transition metal catalysis and organocatalysts.
• Pharmaceutical Intermediate: Used in the research and development of drug delivery systems and as a building block for complex bioactive molecules.
• Separation Science: Functionalized to create stationary phases for chromatography or extraction agents for selective metal ion separation and recovery.
• Nanomaterial Fabrication: Employed as a molecular building block for constructing self-assembled monolayers (SAMs), molecular capsules, and porous organic frameworks.
• Polymer Modification: Incorporated into polymer backbones to impart specific host-guest properties, enhancing material selectivity and functionality.

Basic Information

Item	Details
Product Name	O(1),O(3)-Bis(Ethoxycarbonylmethyl)-O(2),O(4)-Dimethyl-p-tert-Butylcalix[4]Arene
CAS No.	149775-71-3
Molecular Formula	C58H72O8
Molecular Weight	905.19 g/mol
Synonyms	25,27-Bis(ethoxycarbonylmethoxy)-26,28-dimethoxy-p-tert-butylcalix[4]arene; 5,11,17,23-Tetra-tert-butyl-25,27-bis(carbethoxymethoxy)-26,28-dimethoxycalix[4]arene; p-tert-Butylcalix[4]arene-25,27-dicarbethoxy-26,28-dimethyl ether; Calix[4]arene dicarbethoxy dimethyl ether derivative; 1,3-Di(carbethoxymethoxy)-2,4-dimethoxy-p-tert-butylcalix[4]arene; Cone-25,27-bis(ethoxycarbonylmethoxy)-26,28-dimethoxycalix[4]arene
EINECS	Contact for details

Quality Control

Our O(1),O(3)-Bis(Ethoxycarbonylmethyl)-O(2),O(4)-Dimethyl-p-tert-Butylcalix[4]Arene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR (1H & 13C) for structural confirmation, to ensure consistency and meet rigorous research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.