Description

[3R-(3α,4β,4Aα,7α,8β,8Aβ)]-Hexahydro-3-Hydroxy-4,7-Dimethyl-8-(3-Oxobutyl)-1,2-Benzodioxin-8A(3H)-Carboxaldehyde is a complex, high-purity chiral intermediate with significant synthetic utility. Its intricate stereochemistry makes it a valuable building block for the research and development of advanced pharmaceutical compounds, particularly in the synthesis of complex natural products and active pharmaceutical ingredients (APIs). This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of advanced, stereospecific pesticides and herbicides where specific chirality is crucial for bioactivity.
• Fine Chemical Synthesis: Serves as a sophisticated building block for constructing complex molecular architectures in academic and industrial research laboratories.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of chiral molecules.
• Asymmetric Catalysis Studies: Used as a substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.

Basic Information

Product Name	[3R-(3α,4β,4Aα,7α,8β,8Aβ)]-Hexahydro-3-Hydroxy-4,7-Dimethyl-8-(3-Oxobutyl)-1,2-Benzodioxin-8A(3H)-Carboxaldehyde
CAS No.	149588-86-3
Molecular Formula	C16H24O5
Molecular Weight	296.36 g/mol
Synonyms	(3R,3aR,4S,7R,7aS,8R)-Octahydro-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)-1,2-benzodioxine-8-carboxaldehyde; (3R,3aR,4S,7R,7aS,8R)-3-Hydroxy-4,7-dimethyl-8-(3-oxobutyl)hexahydro-1,2-benzodioxine-8-carbaldehyde; Hexahydro-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)-1,2-benzodioxin-8a(3H)-carboxaldehyde, [3R-(3α,4β,4aα,7α,8β,8aβ)]-; 149588-86-3; Chiral Benzodioxane Aldehyde Intermediate; 3-Oxobutyl-substituted Benzodioxane Carboxaldehyde
EINECS	Contact for details

Quality Control

Our [3R-(3α,4β,4Aα,7α,8β,8Aβ)]-Hexahydro-3-Hydroxy-4,7-Dimethyl-8-(3-Oxobutyl)-1,2-Benzodioxin-8A(3H)-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high stereochemical and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and oxidation; store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.