Description

Ethyl 3-Amino-3-(1,3-Benzodioxol-5-Yl)Propanoate Hydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its unique molecular scaffold combining an amino acid ester with a benzodioxole moiety. This compound is critical for the synthesis of complex molecules, offering a versatile chiral building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of central nervous system (CNS) active drugs and other therapeutic agents.
• Medicinal Chemistry Research: Serves as a crucial building block for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), particularly those requiring a β-amino acid ester derivative.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical companies offering bespoke synthesis services to the pharmaceutical industry.

Basic Information

Product Name	Ethyl 3-Amino-3-(1,3-Benzodioxol-5-Yl)Propanoate Hydrochloride
CAS No.	149498-94-2
Molecular Formula	C12H15NO4·HCl
Molecular Weight	273.71 g/mol
Synonyms	Ethyl 3-Amino-3-(1,3-benzodioxol-5-yl)propionate Hydrochloride; 3-Amino-3-(1,3-benzodioxol-5-yl)propionic Acid Ethyl Ester Hydrochloride; 3-(1,3-Benzodioxol-5-yl)-3-aminopropionic Acid Ethyl Ester HCl; Ethyl 3-Amino-3-(benzo[d][1,3]dioxol-5-yl)propanoate Hydrochloride; 3-(Benzo[d][1,3]dioxol-5-yl)-3-((ethoxycarbonyl)amino)propanoic Acid (Related); Piperonyl Aminopropionate Ester Hydrochloride (Common Name)
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-3-(1,3-Benzodioxol-5-Yl)Propanoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral purity assessment, and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.