Description

Spinosyn D Aglycone is a key chemical intermediate derived from the natural fermentation products of the soil bacterium *Saccharopolyspora spinosa*. This compound is of significant commercial and research interest as the core structural aglycone of the spinosyn family of insecticides. It serves as a critical building block for the synthesis and study of novel insect control agents, particularly in the development of next-generation, environmentally benign pesticides. This high-purity intermediate is essential for agrochemical R&D laboratories and manufacturers focused on creating innovative crop protection solutions.

Application

• Agrochemical Research & Development: Primary use as a precursor for the semi-synthesis of novel spinosyn-based insecticides and acaricides.
• Active Ingredient Synthesis: Serves as the core aglycone for constructing spinetoram, spinosad, and other advanced insect control active ingredients.
• Mode of Action Studies: Used in biochemical and pharmacological research to investigate the unique nicotinic acetylcholine receptor (nAChR) targeting mechanism of spinosyns.
• Reference Standard: Employed as an analytical standard in HPLC and LC-MS methods for quality control of spinosyn products and metabolite identification.
• Structure-Activity Relationship (SAR) Studies: Fundamental for medicinal chemistry programs aimed at optimizing the biological activity and environmental profile of insecticidal compounds.

Basic Information

Product Name	Spinosyn D Aglycone
CAS No.	149439-79-2
Molecular Formula	C₂₈H₄₀O₇
Molecular Weight	488.62 g/mol
Synonyms	Spinosyn D Aglycone; Spinosyn D Pseudaglycon; 17-O-Demethyl-17-oxospinosyn A; (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-2-[(6-Deoxy-2,3,4-tri-O-methyl-α-L-mannopyranosyl)oxy]-13-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-9-ethyl-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,16a,16b-heptadecah-14-methyl-1H-cyclopenta[a]phenanthrene-7,15-dione; Spinosyn A Aglycone (common misnomer); Spinosad Aglycone D
EINECS	Contact for details

Quality Control

Our Spinosyn D Aglycone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP standards for advanced intermediate production, ensuring suitability for use in regulated agrochemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single impurity ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.