Description

14-Ethyl-9-(1-(Hexyloxy)Ethyl)-4,8,13,18-Tetramethyl-20-Oxo-3-Phorbine Propanoic Acid is a high-purity synthetic chlorin derivative, a critical intermediate in the development of advanced photosensitizers. Its value lies in its precisely engineered structure, which provides a stable and tunable platform for photodynamic therapy (PDT) research and pharmaceutical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors working on next-generation light-activated therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel photosensitizer drugs used in Photodynamic Therapy (PDT) for cancer treatment.
• Biomedical Research: Used in academic and industrial R&D to study mechanisms of photodynamic action, cellular uptake, and efficacy of new therapeutic agents.
• Photosensitizer Development: Serves as a core structure for creating second and third-generation photosensitizers with improved tissue selectivity and reduced skin photosensitivity.
• Diagnostic Agent Precursor: Potential use in the synthesis of agents for fluorescence-guided surgery or photodiagnosis.
• Advanced Material Synthesis: Can be incorporated into polymers or nanoparticles to create light-harvesting materials or sensors.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	14-Ethyl-9-(1-(Hexyloxy)Ethyl)-4,8,13,18-Tetramethyl-20-Oxo-3-Phorbine Propanoic Acid
CAS No.	149402-51-7
Molecular Formula	C39H50N4O5
Molecular Weight	654.84 g/mol
Synonyms	Hexyloxyethyl Chlorin e6; 9-(1-Hexyloxyethyl)-14-ethyl-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid; Chlorin e6 hexyl ether derivative; 3-Devinyl-3-(1-hexyloxyethyl)pyropheophorbide a; HPPH precursor; Photochlor intermediate; Synthetic Chlorin; Light-activated therapeutic intermediate
EINECS	Contact for details

Quality Control

Our 14-Ethyl-9-(1-(Hexyloxy)Ethyl)-4,8,13,18-Tetramethyl-20-Oxo-3-Phorbine Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, store at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Dark green to black solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC, Area %)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%, Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.