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((R)-(+)-2,2'-Bis(Diphenylphosphin)-1,1' -Binaph)(1,5-Cyclooct)Rh(I)Clo4/Thf Add CAS NO 149368-07-0


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CAS No.:149368-07-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

((R)-(+)-2,2'-Bis(Diphenylphosphin)-1,1' -Binaph)(1,5-Cyclooct)Rh(I)Clo4/Thf Add is a high-purity, chiral rhodium complex widely recognized as a highly effective asymmetric hydrogenation catalyst. Its value lies in enabling the production of enantiomerically pure intermediates, which are critical for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable and selective catalysts for complex synthetic routes.

Application

  • Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
  • Pharmaceutical Manufacturing: Key in the production of chiral drugs, including β-blockers, antibiotics, and anti-inflammatory agents.
  • Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Fine Chemical Production: Enables the synthesis of high-value chiral building blocks for flavors, fragrances, and advanced materials.
  • Academic & Industrial R&D: A vital tool for methodological development in organic synthesis and catalysis research.
  • Process Chemistry Optimization: Employed in scaling up laboratory reactions to efficient, industrial-scale manufacturing processes.

Basic Information

Product Name ((R)-(+)-2,2'-Bis(Diphenylphosphin)-1,1' -Binaph)(1,5-Cyclooct)Rh(I)Clo4/Thf Add
CAS No. 149368-07-0
Molecular Formula C52H48ClO4P2Rh • (C4H8O)x
Molecular Weight Contact for details
Synonyms (R)-BINAP-Rh(I)-COD Perchlorate THF Adduct; (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl(1,5-cyclooctadiene)rhodium(I) Perchlorate Tetrahydrofuran Adduct; (R)-BINAP-Rh(COD)ClO4/THF; Rh-(R)-BINAP Catalyst; (R)-BINAP-Rh(I) Complex; (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl(cyclooctadiene)rhodium Perchlorate THF Adduct; Asymmetric Hydrogenation Catalyst Rh-BINAP
EINECS Contact for details

Quality Control

Every batch of our chiral catalyst is produced and tested under strict quality management protocols to ensure consistent high performance and purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as Rhodium content, chiral purity (enantiomeric excess), and solvent content. Our quality systems support compliance with cGMP standards for pharmaceutical applications, ensuring traceability and reliability for critical manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will compromise its catalytic activity.

Specification

Item Specification
Appearance Orange to red-brown crystalline powder or solid
Identification (IR) Conforms to structure
Rhodium (Rh) Content Contact for details
Purity (HPLC) ≥ 95%
Solvent Content (THF) Contact for details
Moisture (KF) < 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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