Description

Heparin Disaccharide I-P, Sodium Salt is a defined, low molecular weight oligosaccharide derived from the enzymatic or chemical depolymerization of heparin. This compound serves as a critical reference standard and research tool for the structural analysis and functional study of heparin and heparan sulfate glycosaminoglycans. It is essential for scientists and quality control laboratories in the pharmaceutical and biotechnology sectors who require precise materials for method development, calibration, and biological activity research.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the identification, assay, and impurity profiling of low molecular weight heparins (LMWHs) and related products.
• Enzymology & Biochemistry Research: Serves as a specific substrate or inhibitor for studying the activity of heparinases, sulfatases, and other glycosaminoglycan-degrading enzymes.
• Structural Analysis: Critical for calibrating analytical techniques such as High-Performance Liquid Chromatography (HPLC), Capillary Electrophoresis (CE), and Mass Spectrometry (MS) in glycan mapping.
• Biological Activity Studies: Employed in research to investigate the structure-activity relationship (SAR) of heparin fragments in processes like anticoagulation, cell signaling, and growth factor binding.
• Quality Control & Method Validation: Provides a known entity for validating analytical methods in compliance with Good Manufacturing Practice (GMP) and pharmacopeial guidelines (USP/EP).
• Diagnostic Kit Development: Used in the development and calibration of in-vitro diagnostic assays for heparin monitoring and related clinical tests.

Basic Information

Product Name	Heparin Disaccharide I-P, Sodium Salt
CAS No.	149368-05-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	δUA-GlcNS,6S; 2-O-Sulfo-α-L-iduronic acid-(1→4)-2-deoxy-2-sulfamino-6-O-sulfo-α-D-glucopyranose, Sodium Salt; Heparin disaccharide I-P; IdoA(2S)-GlcNS(6S); Disaccharide I-P (Heparin); Sodium Heparin Disaccharide I-P; AUA-GlcNS,6S; α-L-IdoA2S-(1→4)-α-D-GlcNS6S Sodium Salt
EINECS	Contact for details

Quality Control

Our Heparin Disaccharide I-P, Sodium Salt is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and reference standard applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.